Furthermore, the Western blot was performed and the results showed that the total expression of AKT, FAK, and mTOR were not changed, but the expression levels of p-AKT, p-FAK, and p-mTOR were significantly downregulated in si-MAGP1-1 /si-MAGP1-2 transfected GC cells. The gene discussed is PTK2; the disease is gastric cancer.