In CRC, lncRNA p53 upregulated regulator of p53 levels (PURPL) blocks the assembly of the Myb-binding protein 1A (MYBBP1A)-p53 complex by binding to the p53-stabilizing protein MYBBP1A, thereby weakening the cell bank of p53 (24). This evidence concerns the gene MYBBP1A and colorectal carcinoma.