Moreover, we demonstrated the involvement of HMGA2-AS1 in cancer cell motility using PC3 cell line silenced with both siRNAs (Supplemental Figure 6A) and overexpressing A2-AS1_H transcript variant in BX-PC3 (Supplemental Figures 6B,C), a pancreatic cell line that we showed expressing low level of all HMGA2-AS1 transcript variants (see Figure 3A). This evidence concerns the gene HMGA2 and cancer.