ASXL1 and cholangiocarcinoma: We then verified the expression level of KMT2C, ASXL1, and MCM8 in CCA using the GEPIA database and found that all of the three genes, especially ASXL1 (p < 0.05) and MCM8 (p < 0.05), were overexpressed in tumor tissues (Figures 2C–E).