For instance, miR-135a-5p promoted the progression of head and neck squamous cell carcinoma by targeting HOXA10 (Guo et al., 2018), the progression of thyroid carcinoma by VCAN (Zhao et al., 2017), and the progression of gastric cancer by KIFC1 (Zhang et al., 2016). This evidence concerns the gene KIFC1 and head and neck squamous cell carcinoma.