The immunoglobulin M-specific capture enzyme-linked immunosorbent assay (ELISA) (MAC-ELISA) is the standard serological test for the detection of anti-DENV IgM antibodies (WHO, 2009), and various dengue diagnostic tests are commercially available (Panbio Dengue IgM capture kit, Panbio Dengue duo cassette, Pathozyme dengue M capture and Dengue Vírus IgM Capture DxSelectTM EL1500M). Here, CD40LG is linked to dengue disease.