IL17A and coronary artery disorder: Finally, evidence that IL-17A might also have atheroprotective effects also exists (Figure 1D): low serum levels of IL-17A have been associated with a higher risk of cardiovascular recurrences in coronary artery disease patients, an observation which might suggest that IL-17A might exert some form of preconditioning-like protection, and a murine IL-17A knockout model conferred resistance to high-fat diet-induced weight gain (102).