CD40LG and ophthalmoplegia: These include: (a) antibodies against a dialosyl epitope, a sequence contained in GD1b, GD3, GT1b, and GQ1b molecules in patients with a paraproteinemic neuropathy defined as CANOMAD (Chronic Ataxic Neuropathy, Ophthalmoplegia, IgM paraprotein, cold Agglutinin, Disialosyl antibodies) (56, 57); (b) GM1 IgM-Abs in patients with motor multifocal neuropathy with conduction blocks (MMN) (58); (c) GQ1b (with/without GT1a) IgG antibodies in patients with Fisher syndrome, a variant of Guillain-Barrè syndrome (GBS) with ophthalmoplegia and ataxic neuropathy (59, 60).