P2RY1 and status epilepticus: To determine whether targeting of P2Y1 also impacts on HFHA spiking and thereby potentially on seizure-induced neurodegeneration, we re-analyzed EEG traces and quantified HFHA spiking in mice subjected to intraamygdala KA and treated with the P2Y1 agonist MRS23 or P2Y1 antagonist MRS25 15 min following the induction of status epilepticus (Alves et al., 2019).