In contrast, a recent study on samples from seven HD cases (Vonsattel grades 3 and 4), failed to detect TNIs (Baskota et al., 2019) and they reasoned that this may be due to technical features because the variety of antibodies they used did not detect neurons with cytoplasmic Tau staining, which are the ones displaying TNIs in the above-mentioned studies which do detect them. This evidence concerns the gene MAPT and Huntington disease.