A549 is a relatively TRAIL‐resistant NSCLC cell line 23, while HCT116 is a TRAIL‐sensitive model of colorectal cancer, and DU145 is a classical model of androgen‐independent prostate cancer representing a later stage of the disease and which typically expresses high levels of FLIP 24. This evidence concerns the gene TNFSF10 and non-small cell lung carcinoma.