In this sense, oncogenic lncRNA FOXD1-AS1 (FOXD1-antisense 1), the antisense transcript of the gene FOXD1, was reported to interact with miR339-5p and miR342-3p [197], tumor suppressor TP73-AS1 sponged miR-941 [198], while TSPAN31, the natural antisense transcript of cyclin dependent kinase 4 (CDK4), interacted with miR-135b in hepatocellular carcinoma causing TSPAN31 silencing and the subsequent upregulation of CDK4 [199]. The gene discussed is FOXD1; the disease is hepatocellular carcinoma.