In conclusion, QFAE had an effective anti-inflammation in LPS-induced RAW 264.7 cells and lung phylactic activity in LPS-stimulated ALI mice that saliently alleviated the pro-inflammatory cytokines TNF-α, IL-6, and IL-1β, while noticeably raised the anti-inflammatory cytokine IL-10 in vitro and in vivo. Here, IL1B is linked to acute respiratory distress syndrome.