Three AMD-associated genes (BCAR1, CFDP1, and TMEM170A) residing within a locus on chromosome 16 (chr16:75233867-75516739), coincide with GWAS signals of six different trait groups, namely “organ function”, “cancer”, “neurological diseases”, “autoimmune diseases”, “metabolic traits”, and “AMD”. The gene discussed is CFDP1; the disease is autoimmune disease.