Familial hypercholesterolemia (FH) is an autosomal dominant disease primarily caused by mutations in the low-density lipoprotein (LDL) receptor (LDLR) gene, leading to premature cardiovascular disease (CVD) (Gidding, 2016; Goldstein and Brown, 2009; Varret and Rabes, 2012). Here, LDLR is linked to familial hypercholesterolemia.