GRHL2 suppresses EMT and has an expression pattern inversely correlated with that of ZEB1 in numerous cancers (Chen et al., 2016; Chung et al., 2016; Nishino et al., 2017; Paltoglou et al., 2017; Pan et al., 2017; Quan et al., 2014; Werner et al., 2013; Xiang et al., 2017). This evidence concerns the gene ZEB1 and cancer.