Dick et al (2010) [36] provided evidence for the involvement of 23 genes (NTSR2, TRIB2, PPM1G, MEM01, HAAO, MTIF2, CCDC139, EHBP1, BUB1, TTL, CKAP2L, MGAT5, ARHGAP15, KIAA1189, COBLLI, FAM130A2, LPR2, CHN1, PRKRA, PPP1R1C, LOC402117, IL8RA, FARP2) on chromosome 2 in alcohol dependence. Here, BUB1 is linked to alcohol dependence.