In the subgroup analysis by GN type only the IgAN patients (n = 82) showed significant difference in the C3 deposition between patients with different genotypes: 100% of patients with the C3FF genotype, 97% of those withC3FS genotype and 64% of those with the C3SS genotype had C3 deposition in their biopsies, p = 0.002 (Table 7). This evidence concerns the gene C3 and ganglioneuroma.