Based on these observations, we first summarized a list of leukocyte migration related genes (Supplementary Table 1) [23, 28] and analyzed the correlation between these genes and clinical pathological features, including tumor purity, immune score, stromal score, isocitrate dehydrogenase 1(IDH1) status, and subtypes, with CGGA and TCGA GBM RNA sequencing datasets. This evidence concerns the gene IDH1 and neoplasm.