Globally, regardless of diabetes type, many people treated with insulin struggle to take their medication on time and also maintain their treatment regimen over extended periods of time.1–4 Difficulties with insulin dosing and inaccurate dose timing have been shown to result in poor glycemic control for people with diabetes.5,6 The impact of missed insulin injections on HbA1c levels is well established,7–12 leading to an increasing risk of diabetes-related complications.13,14. This evidence concerns the gene INS and diabetes mellitus.