FASN and hepatocellular carcinoma: For instance, the targeted combination of miRNA1207‐5p with FASN inhibits HCC invasion via inhibiting the Akt/mTOR signalling pathway, whereas FASN up‐regulation reverses the inhibition of miRNA‐1207‐5p on HCC cells.25, 26 Research conducted by Wu et al27 revealed a mechanism by which microRNA‐21, in part, promoted hepatic lipid accumulation and HCC tumour progression by interacting with the HBP1‐p53‐SREBP1c pathway and suggested the potential therapeutic value of microRNA‐21‐anti‐sense oligonucleotide.