The bioenergetic and synthetic demands for DCs to fluctuate extensively, and the build‐up of intracellular LDs, may reflect a recent surplus of energy, and an actively changed metabolic programme.109 Cubillos‐Ruiz et al110 deemed that tumour‐derived factors triggered lipid peroxidation in TADCs, which activated the endoplasmic reticulum (ER) stress response mediated by the inositol‐requiring protein 1α(IRE‐1α) as well as its target X‐box binding protein 1 (XBP1). The gene discussed is XBP1; the disease is neoplasm.