On the other hand, the expression of phosphorylated AMPK is negatively correlated with the Ki‐67 level (a cell proliferation marker), tumour grade and tumour size in HCC, as mentioned above, thus indicating that the high FAO level mediated by AMPK may be considered as a favourable factor.20 In summary, these observations uncover the distinct differences in lipid metabolism within HCC that stem from the high inter‐tumour heterogeneity, which are associated with patient survival. The gene discussed is MKI67; the disease is hepatocellular carcinoma.