To investigate the relationship among tumorinfiltrating M2 macrophages and angiogenesis and lymph node metastasis, IHC experiments were performed for the evaluation of microvessel density (MVD) and lymphatic microvessel density (LMVD) via staining of CD31 and LYVE-1 in 15 samples of both groups. Here, LYVE1 is linked to metastatic malignant neoplasm in the lymph nodes.