The impact of ILP on overall survival has not yet been documented in larger studies; however, ILP carries a complete response (CR) rate, referring to the complete disappearance of tumors after 3 months, of 50–70%.10,11 Patients often experience tumor regression during several months after perfusion,12 which implies that the treatment may comprise activation of anti-tumoral immunity. This evidence concerns the gene XIAP and neoplasm.