CXCL10 is primarily induced by IFN-γ in monocytes, endothelial cells and fibroblasts.5 Its cognate receptor, CXCR3, is expressed by activated T cells and NK cells6,7 but may also be expressed by melanoma cells.8,9 CCR4 interacts with CCL2, CCL4 and CCL5, while CCR5 interacts with CCL4 and CCL5. The gene discussed is CXCR3; the disease is melanoma.