Compared with PBMCs from healthy controls, melanoma patients harbored CD4+ T cells and NK cells with higher expression of CXCR3 (Figure 3(a,b)) along with NK cells, CD4+ T cells and CD8+ T cells with higher expression of the receptors CCR4 and CCR5 (Figure 3(d–i)). This evidence concerns the gene CCR4 and melanoma.