On univariate analyses, tumour staging (T3–4 vs T2; p = 0.0001), Ki-67 at surgery (>10% vs ≤10%; p = 0.0093), pathological tumour size (pT3–4 vs pT1–2; p = 0.0012), node status (pN positive vs negative; p = 0.0004), adjuvant chemotherapy (yes vs no; p = 0.0167) and PEPI group (III vs I + II; p = 0.0004) were associated with RFS. This evidence concerns the gene MKI67 and neoplasm.