LIGHT has been reported to normalize the intratumoral vessels, promote antitumor immunity through stimulating the secretion of chemoattractants recruiting lymphocytes (CCL21 and CXCL13), inhibit Treg-mediated immune-supression27–29, and induce the tertiary lymphoid structures (TLSs) to support the local generation of tumor-specific immune responses29,30. Here, TNFSF14 is linked to neoplasm.