LCN2 and cerebrovascular disorder: Additional association analyses of LCN2 and MMSE scores including all groups with cerebrovascular disease (SVDND, VCIND, and VaD) showed highly significant negative correlations in cohort 1 (cc = −0.55, p < 0.0001, Fig. 3c, Spearman correlation test) and cohort 4 (cc = −0.56, p = 0.008, Fig. 3d, Spearman correlation test).