LCN2 and Alzheimer disease: LCN2 was able to discriminate AD from VaD (AUC = 0.9, 95% CI: 0.82–0.98, p < 0.001, z test with H0: AUC = 0.5 in all cases) with a sensitivity of 82% and a specificity of 87%, as well as ND from VaD with a sensitivity of 78% and a specificity of 82%.