When evaluating the relationship between immune markers and the tumor T cell repertoire, T cell density and richness were correlated with CD3 (r = 0.53; p < 0.0001 and r = 0.30; p = 0.0004, Spearman rank correlation), CD4 (r = 0.39; p < 0.0001 and r = 0.33; p < 0.0001, Spearman rank correlation), and CD8 (r = 0.51; p < 0.0001 and r = 0.27, p = 0.002, Spearman rank correlation), as anticipated (n = 146; Supplementary Fig. 3A–F). Here, CD4 is linked to neoplasm.