Particularly, the ATR gene was significantly upregulated in these cells (Fig. 3d, Supplementary Table 1) as well as in 14 MYB-positive, ACC patient specimens (qPCR) and in eight ACC PDX models (RNA-seq) compared with normal salivary gland tissues (Fig. 3e, Supplementary Fig. 4). This evidence concerns the gene MYB and adrenal cortex carcinoma.