The H&E, TUNEL and IHC staining of Ki-67 results showed that there were less necrotic (pink areas) and apoptotic areas (the nucleus was stained dark-brown), but more tumor parenchyma and higher Ki-67 staining in the LM3-SR groups (Fig. 2d), as well as a reduced treatment effect of Sora (10 mg/kg). The gene discussed is MKI67; the disease is neoplasm.