TNF and infection: Looking at the cytokine levels, there was observed up regulation of pro-inflammatory TNF-α induced proteins (TNFAIP6 [log2FC 2.6], TNFAIP8 [log2FC 5.3]) involved in systemic inflammation; and also, elevation of interleukins IL21 (Log2FC 3.7) and IL1 receptor (Log2FC 2.0) that respond to infection.