PMS1 and malignant pleural mesothelioma: Betti et al recently reported a novel truncated germline PMS1 mutation (c.1380delT, p.Ser460fs) that may predispose malignant pleural mesothelioma.[30] Other germline mutations of PMS1, mostly SNV mutations, were interpreted as benign or with unknown significance[31–34] (Table 1).