MYC and Burkitt lymphoma: As the research continued, the scholars realized the MYC gene interacted with immunoglobulin (IG) heavy-chain locus.[4,5] Till now, it is considered that the abnormal expression of MYC gene, mostly triggered by t(8;14)(q24;q32) translocation, is a mechanism behind BL.[6,7] C-myc is a proto-oncogene at 8q24 and IgH is an immunoglobulin heavy chain gene at 14q32.