VSIG4 and cancer: Its aberrant expression in GBM is noted to regulate cancer cell proliferation, apoptosis and invasiveness through downstream influence on multiple genes.34 Zhang et al further elucidated that the up‐regulation of let‐7g‐5p inhibits cell invasion and migration in GBM U‐87MG cells, acting via a reduction in VSIG4.10 HMGA2 is generally considered as a tumour promoter gene in several cancers.