In contrast, overexpression of CISAL inhibited tumor growth and enhanced cisplatin sensitivity (Figures 6F–6H), whereas apoptotic tumor cells, CISAL, BRCA1, miR-593-5p, and MFF expression (Figures 6I and S12A–S12E), were also detected, supporting the idea that enforced CISAL expression inhibits BRCA1 transcription in vivo. The gene discussed is BRCA1; the disease is neoplasm.