Other identified genes previously reported in GWAS to be associated with CVD-related traits were ELL2 (GWAS of BP [17], insulin [22] and glucose [22]), TRPS1 (GWAS of BP [17]), PID1 (GWAS of stroke [23], lung function [24] and chronic obstructive pulmonary disease [25]) and WIPF1 (GWAS of resting heart rate [26]). The gene discussed is INS; the disease is chronic obstructive pulmonary disease.