It is known that tumor heterogeneity is frequent in cancer.55, 56 In this study, AXL‐expressing VIM‐positive CTCs were detected in 60% of patient samples and all except one of them also contained AXL‐negative VM‐positive CTCs, suggesting that there is heterogeneity of AXL expression on CTCs in a single patient. The gene discussed is AXL; the disease is neoplasm.