That is, differential expressions of 5 genes among Solute carrier organic anion transporter family member 4C1(SLCO4C1), ElaC ribonucleaseZ1(ELAC1), Hepatic leukemia factor (HLF), Zinc finger protein 204, pseudogene (ZNF204P), and ST3 beta-galactoside alpha-2,3-sialyltransferase 5 (ST3GAL5) will influence progression-free survival and survival time of NSCLC patients. The gene discussed is HLF; the disease is non-small cell lung carcinoma.