CEACAM5 and rectal cancer: When multivariate Cox analysis was performed, we convinced the following clinicopathological characteristics as independent prognostic factors in stage I–II rectal cancer; these included race, gender, tumor location, age at diagnosis, tumor grade, T stage, and serum CEA level, while the risk between T2,C0 and T1,C0 was not statistical difference (P = 0.925).