Future studies on C. perfringens sialidases may also involve investigating the following aspects: (1) the relationship between various systems involved in the regulation of sialidases; (2) the roles of sialidase NanH and NanJ in intestinal infections caused by C. perfringens and whether NanH, NanI, and NanJ have synergistic effects; (3) the differences in the specific sialidases produced by epidemiologically different strains of C. perfringens. This evidence concerns the gene NEU1 and digestive system infectious disorder.