For both head and neck squamous cell carcinoma (HNSC) and ovarian cancer (OV), FUNDC1 significantly influenced their overall survival (HNSC: OS, HR = 1.34, 95% CI from 1.02 to 1.75, logrank P = 0.034; OV: OS, HR = 0.66, 95% CI from 0.49 to 0.88, logrank P = 0.0047) but not relapse-free survival (HNSC: RFS, HR = 1.49, 95% CI from 0.7 to 3.17, logrank P = 0.29; OVC: RFS, HR = 0.74, 95% CI from 0.52 to 1.06, logrank P = 0.095) (Figures 3G–J). Here, FUNDC1 is linked to head and neck squamous cell carcinoma.