Among them, FUNDC1 played a detrimental role in five cancer types, including brain (OS: total number = 74, HR = 4.05, Cox P = 0.007261), breast [DMFS (distant metastasis-free survival): total number = 77, HR = 5.33, Cox P = 0.039723], colorectal [DFS (disease-free survival): total number = 55, HR = 2.48, Cox P = 0.015719; DSS (disease-specific survival): total number = 49, HR = 2.14, Cox P = 0.043165], head and neck [RFS (relapse-free survival): total number = 28, HR = 2.32, Cox P = 0.022573], and skin cancers (OS: total number = 38, HR = 4.29, Cox P = 0.031662). The gene discussed is FUNDC1; the disease is skin neoplasm.