High EMT (HR = 2.19, p = 0.0014), EGFR (HR = 1.82, p = 0.0038), acute hypoxia (HR = 1.64, p = 0.017), DNA CL repair defect (HR = 1.8, p = 0.0085) and chronic hypoxia scores (HR = 1.7, p = 0.015) and tumor volumes (HR = 1.72, p = 0.036) are associated with a worse progression free survival (PFS) (Supplementary Figure 7; Supplementary Table 3). Here, EGFR is linked to neoplasm.