However, patients who presented with distant disease were more likely to be black (p = 0.002), more likely to have a serum PSA level ≥20 ng/ml (p < 0.001), less likely to have low tumor grade (well-differentiated or moderately differentiated tumors) (p < 0.001), and less likely to undergo surgical resection (p < 0.001). Here, KLK3 is linked to neoplasm.