When B7-H3 expression in tumor cells (tumor B7-H3) was correlated with the clinicopathological data, we found higher tumor volume (P = 0.023), tumor stage (P = 0.002), tumor depth (P = 0.001), and lymph node involvement (P = 0.006) as well as a lower survival (P = 0.020) in the group with high expression of tumor B7-H3 (Table 1). This evidence concerns the gene CD276 and neoplasm.