Finally, digging deeper to explore a correlation between lncRNAs XIST, TSIX, and PD-L1 expression in BC patients, TNBC cells (MDA-MB231 cells) were transfected with siRNAs for both lncRNAs XIST and TSIX followed by monitoring their knockdown impact on PD-L1 expression. The gene discussed is CD274; the disease is breast cancer.