Recently, a group of RBPS termed MEX-3 RNA binding family member (MEX3) was identified in the nematode Caenorhabditis elegans (Ciosk, DePalma & Priess, 2006) and revealed one of the few RBPs with carcinogenic or tumor suppressor activity (Kim, Hur & Jeong, 2009; Pereira et al., 2013a). Here, MEX3D is linked to neoplasm.