Mutations of different genes like MITF (microphthalmia-associated transcription factor), PAX3 (Paired Box Gene 3), SOX10, and EDNRB (endothelin receptor type B, gene) have been noted in causing mild or incomplete phenotypic expression of symptoms in Waardenburg syndrome (Wildhardt et al. 2013). The gene discussed is MITF; the disease is Waardenburg syndrome.