On the addition of ln(IL-4) and ln(IL-17) to the standard model (age, sex, and LVEF), the corrected area under the curve increased from 0.9155 (95% CI, 0.8769-0.9540) to 0.9344 (95% CI, 0.8948-0.9741) for predicting the incidence of DCM events. The gene discussed is IL17A; the disease is familial dilated cardiomyopathy.