TLR7 and systemic lupus erythematosus: This TLR7-inducible model was first published in 2014 and has since gained popularity because disease induction is rapid (shorter than pristane-induced lupus-like disease, which is also TLR7-mediated), and the lupus phenotype is principally dependent on pDCs/Type I IFNs, which are of import in human disease.