Additionally, albuminuria was not correlated with mortality (Figure 3B), and no significant difference was seen between 3 and 5 weeks after treatment (Figure 3C), suggesting this low level of proteinuria is enhanced in TLR7-stimulated lupus-prone mice, but is not rapidly progressive, nor the cause of death in the young TLR7- stimulated mice. The gene discussed is TLR7; the disease is systemic lupus erythematosus.