HLA-DRB1 and Langerhans cell histiocytosis: Moreover, our results neither confirm that LCH-patients with unifocal bone disease have significantly more often HLA-DR4 and/or HLA-Cw7 (66) subtypes nor that patients with single-system LCH have an increased prevalence of HLA-DRB1*03 (67) when compared to patients with multisystem LCH (Table S4 and Figure S5, respectively).