Finally, Hosseini et al. observed a lower frequency of acute GvHD (grade II or more; p = 0.02) and extensive chronic GvHD (p = 0.04) (14), besides also a lower TRM and better OS in 56 patients with HLA-E*01:03/01:03 genotype (16). The gene discussed is HLA-E; the disease is graft versus host disease.